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正常肠道活检组织及未经治疗的乳糜泻患者肠道活检组织中的肠激酶。

Enterokinase in normal intestinal biopsies and those from patients with untreated coeliac disease.

作者信息

Woodley J F, Keane R

出版信息

Gut. 1972 Nov;13(11):900-2. doi: 10.1136/gut.13.11.900.

Abstract

Enterokinase was measured in peroral intestinal biopsies showing normal histology and in those from untreated coeliac patients which showed gross villous atrophy. There was no significant difference in the specific activity of enterokinase between these two groups. These results do not support the recent hypothesis that enterokinase is a brush border enzyme, but would be consistent with the idea that it is adsorbed to the cell membrane following secretion.

摘要

在组织学正常的经口肠道活检样本以及未经治疗的乳糜泻患者(表现为明显绒毛萎缩)的肠道活检样本中测定了肠激酶。两组之间肠激酶的比活性没有显著差异。这些结果不支持最近关于肠激酶是一种刷状缘酶的假说,但与分泌后它吸附在细胞膜上的观点一致。

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本文引用的文献

2
Jejunal biopsy in celiac disease.乳糜泻的空肠活检
Clin Pediatr (Phila). 1968 Sep;7(9):544-52. doi: 10.1177/000992286800700910.
3
Assay of intestinal disaccharidases.肠道双糖酶测定
Anal Biochem. 1968 Jan;22(1):99-107. doi: 10.1016/0003-2697(68)90263-7.
4
Enterocyte in coeliac disease. 1.乳糜泻中的肠上皮细胞。1.
Br Med J. 1970 Sep 26;3(5725):725-31. doi: 10.1136/bmj.3.5725.725.
5
The cellular localization of enterokinase.肠激酶的细胞定位。
Biochim Biophys Acta. 1970 Mar 18;198(3):621-2. doi: 10.1016/0005-2744(70)90144-0.
6
Assay of intestinal disaccharidases.肠道双糖酶测定
Enzymol Biol Clin (Basel). 1970;11(1):52-66.
9
Immunohistochemical localization of enterokinase in the porcine intestine.肠激酶在猪肠道中的免疫组织化学定位
Okajimas Folia Anat Jpn. 1971 Jun;48(1):15-23 passim. doi: 10.2535/ofaj1936.48.1_15.

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