Woodley J F, Keane R
Gut. 1972 Nov;13(11):900-2. doi: 10.1136/gut.13.11.900.
Enterokinase was measured in peroral intestinal biopsies showing normal histology and in those from untreated coeliac patients which showed gross villous atrophy. There was no significant difference in the specific activity of enterokinase between these two groups. These results do not support the recent hypothesis that enterokinase is a brush border enzyme, but would be consistent with the idea that it is adsorbed to the cell membrane following secretion.
在组织学正常的经口肠道活检样本以及未经治疗的乳糜泻患者(表现为明显绒毛萎缩)的肠道活检样本中测定了肠激酶。两组之间肠激酶的比活性没有显著差异。这些结果不支持最近关于肠激酶是一种刷状缘酶的假说,但与分泌后它吸附在细胞膜上的观点一致。