Pont A, Gutierrez-Hartman A
Arch Intern Med. 1979 Aug;139(8):938-40. doi: 10.1001/archinte.139.8.938.
In December 1976, an 18-year-old woman had symptoms typical of Cushing's syndrome. Laboratory evaluations and roentgenograms documented pituitary-dependent Cushing's disease in a patient with a pituitary microadenoma. In May 1977, she underwent transsphenoidal pituitary exploration. A 2-mm pituitary microadenoma was removed. The patient improved, and laboratory evaluation documented remission of the disease. In June 1978, she again complained of symptoms compatible with Cushing's disease. Laboratory evaluation confirmed a pituitary-dependent hypercortisonism. This case report marks the first recurrence of Cushing's disease in a patient previously cured by transsphenoidal resection of a pituitary tumor.
1976年12月，一名18岁女性出现了库欣综合征的典型症状。实验室检查和X光片证实该患者患有垂体微腺瘤导致的垂体依赖性库欣病。1977年5月，她接受了经蝶窦垂体探查术。切除了一个2毫米的垂体微腺瘤。患者病情好转，实验室检查证明疾病缓解。1978年6月，她再次诉说出现了与库欣病相符的症状。实验室检查证实存在垂体依赖性皮质醇增多症。本病例报告标志着一名先前经蝶窦切除垂体肿瘤治愈的患者首次出现库欣病复发。
