一种重构的微粒体酶系统，该系统通过萘-1,2-氧化物将萘转化为反式-1,2-二羟基-1,2-二氢萘：环氧化物水解酶存在于细胞色素P-450和P-448组分中。 - Suppr

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超能文献

A reconstituted microsomal enzyme system that converts naphthalene to trans-1,2-dihydroxy-1,2-dihydronaphthalene via naphthalene-1,2-oxide: presence of epoxide hydrase in cytochrome P-450 and P-448 fractions.

作者信息

Oesch F, Jerina D M, Daly J W, Lu A Y, Kuntzman R, Conney A H

出版信息

Arch Biochem Biophys. 1972 Nov;153(1):62-7. doi: 10.1016/0003-9861(72)90420-1.

DOI:10.1016/0003-9861(72)90420-1

PMID:4650623

Abstract

摘要

相似文献

A reconstituted microsomal enzyme system that converts naphthalene to trans-1,2-dihydroxy-1,2-dihydronaphthalene via naphthalene-1,2-oxide: presence of epoxide hydrase in cytochrome P-450 and P-448 fractions.一种重构的微粒体酶系统，该系统通过萘-1,2-氧化物将萘转化为反式-1,2-二羟基-1,2-二氢萘：环氧化物水解酶存在于细胞色素P-450和P-448组分中。

Arch Biochem Biophys. 1972 Nov;153(1):62-7. doi: 10.1016/0003-9861(72)90420-1.

Conversion of naphthalene to trans-naphthalene dihydrodiol: evidence for the presence of a coupled aryl monooxygenase-epoxide hydrase system in hepatic microsomes.萘向反式萘二氢二醇的转化：肝微粒体中存在偶联芳基单加氧酶 - 环氧化物水解酶系统的证据。

Biochem Biophys Res Commun. 1972 Feb 25;46(4):1713-20. doi: 10.1016/0006-291x(72)90807-8.

Substrate specificity of hepatic epoxide hydrase in microsomes and in a purified preparation: evidence for homologous enzymes.

Arch Biochem Biophys. 1971 May;144(1):253-61. doi: 10.1016/0003-9861(71)90476-0.

Reconstituted liver microsomal enzyme system that hydroxylates drugs, other foreign compounds, and endogenous substrates. IV. Hydroxylation of aniline.可使药物、其他外来化合物及内源性底物羟化的重组肝微粒体酶系统。IV. 苯胺的羟化作用。

Arch Biochem Biophys. 1972 Nov;153(1):294-7. doi: 10.1016/0003-9861(72)90447-x.

Assay and partial purification of epoxide hydrase from rat liver microsomes.

Arch Biochem Biophys. 1974 Oct;164(2):511-7. doi: 10.1016/0003-9861(74)90061-7.

Reconstituted liver microsomal enzyme system that hydroxylates drugs, other foreign compounds, and endogenous substrates. VIII. Different catalytic activities of rabbit and rat cytochromes P-448.能够使药物、其他外来化合物和内源性底物发生羟基化反应的重组肝微粒体酶系统。VIII. 兔和大鼠细胞色素P-448的不同催化活性。

Mol Pharmacol. 1975 Mar;11(2):201-10.

Liver microsomal electron transport systems. II. The involvement of cytochrome b5 in the NADH-dependent hydroxylation of 3,4-benzpyrene by a reconstituted cytochrome P-448-containing system.肝脏微粒体电子传递系统。II. 细胞色素b5在由重组含细胞色素P - 448系统催化的3,4 - 苯并芘NADH依赖性羟基化反应中的作用。

Biochem Biophys Res Commun. 1974 May 20;58(2):516-522. doi: 10.1016/0006-291x(74)90395-7.

Partial purification and separation of multiple forms of cytochrome. P-450 and cytochrome P-448 from rat liver microsomes.大鼠肝脏微粒体中细胞色素P-450和细胞色素P-448多种形式的部分纯化与分离

Adv Exp Med Biol. 1975;58(00):1-24. doi: 10.1007/978-1-4615-9026-2_1.

The resolution and reconstitution of the liver microsomal hydroxylation system.肝脏微粒体羟化系统的分解与重组。

Biochim Biophys Acta. 1974 Sep 16;344(2):205-40. doi: 10.1016/0304-4157(74)90004-5.

Hepatic epoxide hydrase. Structure-activity relationships for substrates and inhibitors.肝环氧水解酶。底物和抑制剂的构效关系。

Biochemistry. 1971 Dec 21;10(26):4858-66. doi: 10.1021/bi00802a005.

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J Bacteriol. 1982 Mar;149(3):948-54. doi: 10.1128/jb.149.3.948-954.1982.

Purification and specificity of a human microsomal epoxide hydratase.人微粒体环氧化物水解酶的纯化及特异性

Biochem J. 1974 Apr;139(1):77-88. doi: 10.1042/bj1390077.

Evidence for an NIH shift in oxidation of naphthalene by the marine cyanobacterium Oscillatoria sp. strain JCM.海洋蓝藻颤藻属 Oscillatoria sp. 菌株JCM对萘氧化过程中出现NIH迁移现象的证据。

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Metabolism of naphthalene by Cunninghamella elegans.秀丽小克银汉霉对萘的代谢

Appl Environ Microbiol. 1977 Oct;34(4):363-70. doi: 10.1128/aem.34.4.363-370.1977.

Fungal transformation of naphthalene.萘的真菌转化

Arch Microbiol. 1978 May 30;117(2):135-43. doi: 10.1007/BF00402301.

On the biochemical mechanism of tumorigenesis in mouse skin. VIII. Isolation and characterization of epidermal microsomes and properties of their arylhydrocarbon monooxygenase and epoxide hydr(at)ase.小鼠皮肤肿瘤发生的生化机制。VIII. 表皮微粒体的分离、表征及其芳烃单加氧酶和环氧化物水合酶的性质

Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1977 Dec 15;90(3):259-79. doi: 10.1007/BF00284300.

Bacterial cis-dihydrodiol dehydrogenases: comparison of physicochemical and immunological protperties.细菌顺式二氢二醇脱氢酶：物理化学性质与免疫学性质的比较

J Bacteriol. 1976 Dec;128(3):842-50. doi: 10.1128/jb.128.3.842-850.1976.

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