[Pathohistologic and biochemical changes in the brain in atherosclerotic dementia].

The data obtained from studies of 48 postmortem cases of atherosclerotic dementia with the use of histological and biochemical methods demonstrated a prevalence of ischemic changes in the nervous cells, cells-shadows, demyelinization, fragmentation of nervous filaments, hyperplasia, hypertrophy of astrocytes, a swelling of oligodendroglia compared to other changes. A drop in the amount of lecithin in the brain is the highest, while that in kefaline fractions is the lowest. A drop in the amount of sphyngomyelin occupies a middle place.