Macaya Conde J, Duffau Toro G, Soriano Pérez H, Bernier Villarroel L, Calderón Marín A, Emilfork Soto M, Goldenberg Altsman E, Urbina Romero A M
Bol Med Hosp Infant Mex. 1979 Jul-Aug;36(4):541-58.
Ninety-six infants were studied with water balance technique at the Infant Unit of Hospital Roberto del Río, Santiago de Chile. Sixty-eight with acute diarrhoea and twenty-eight with protracted diarrhoea associated to carbohydrate intolerance. Total water losses in most of them were in the range of 150 to 225 ml/kg day. Stool loses were in the range of 25 to 75 gm/kg/day, with humidity percentage varing from 97.4 to 92.5%. In patients with acute diarrhoea, stool losses and humidity percentage showed slight decreasing tendency in the following balances. By contrast, those with protracted diarrhoea showed a definite decreasing tendency in both parameters. Most infants showed a urinary output in the range of 20 to 80 ml/kg/day. Ten percent showed oliguria. Polyuria was observed occasionally. Insensible water losses were in the range of 50 to 80 ml/kg/day. Most patients showed weight gain of 0.1 to 5.0% in the first balance. Stool acidity and presence of reductant substances (tested by positivity of Fehling reaction) were found in 24% of infants with acute diarrhoea in the first balance. Sodium concentration in stools varied from 40 to 70 mEq/l; and potassium varied between 20 and 40 mEq/l. Bacterial pathogens were isolated in 64% of patients with acute diarrhoea; most of them E. coli enteropathogenic.
在智利圣地亚哥罗伯托·德尔·里奥医院的婴儿科室,采用水平衡技术对96名婴儿进行了研究。其中68名患有急性腹泻,28名患有与碳水化合物不耐受相关的迁延性腹泻。他们中的大多数总失水量在150至225毫升/千克·天之间。粪便失水量在25至75克/千克·天之间,湿度百分比从97.4%至92.5%不等。在急性腹泻患者中,后续几次平衡时粪便失水量和湿度百分比呈轻微下降趋势。相比之下,迁延性腹泻患者的这两个参数呈明显下降趋势。大多数婴儿的尿量在20至80毫升/千克·天之间。10%的婴儿出现少尿。偶尔观察到多尿。不显性失水量在50至80毫升/千克·天之间。大多数患者在首次平衡时体重增加了0.1%至5.0%。在首次平衡时,24%的急性腹泻婴儿粪便呈酸性且存在还原物质(通过费林反应阳性检测)。粪便中的钠浓度在40至70毫当量/升之间;钾浓度在20至40毫当量/升之间。64%的急性腹泻患者分离出细菌病原体;其中大多数是致病性大肠杆菌。