Ginks W, Leatham A, Siddons H
Br Heart J. 1979 Jun;41(6):633-6. doi: 10.1136/hrt.41.6.633.
Between the years 1960 and 1974, 839 patients were paced for chronic complete atrioventricular block. Analysis of survival compared with the general population showed that 170 deaths were expected according to standard mortality tables and 288 actually occurred, giving a ratio of actual to expected deaths of 1.7:1. Patients with a definite history of myocardial infarction showed a higher than average mortality when paced. Mortality was not influenced whether heart was constant or intermittent, whether the ventricular rate was below or above 40/minutes, or whether QRS duration was greater or less than 0.1 second. Analysis of the age groups paced disclosed the most important correlations. Between the ages of 80 and 89 years paced patients could expect to survive as long as other of the same age without heart block. There was, however, a very high ratio of 4.5:1 for 90 patients in the age group 50 to 59 years. The reason for the high mortality ratio was uncertain but it may have been the result of a greater incidence of underlying coronary artery disease.
在1960年至1974年期间，839例患者因慢性完全性房室传导阻滞接受了起搏治疗。与普通人群的生存情况分析表明，根据标准死亡率表预计有170例死亡，而实际发生了288例死亡，实际死亡与预期死亡的比例为1.7:1。有明确心肌梗死病史的患者在接受起搏治疗时死亡率高于平均水平。死亡率不受心脏起搏是持续还是间歇、心室率是低于还是高于40次/分钟，或QRS波时限是大于还是小于0.1秒的影响。对接受起搏治疗的年龄组分析揭示了最重要的相关性。80至89岁接受起搏治疗的患者预期存活时间与其他同龄无心脏传导阻滞的患者相同。然而，50至59岁年龄组的90例患者死亡率高达4.5:1。高死亡率的原因尚不确定，但可能是潜在冠状动脉疾病发生率较高的结果。
