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未被察觉的冠状动脉疾病作为中年慢性房室传导阻滞的病因

Unsuspected coronary artery disease as cause of chronic atrioventricular block in middle age.

作者信息

Ginks W, Sutton R, Siddons H, Leatham A

出版信息

Br Heart J. 1980 Dec;44(6):699-702. doi: 10.1136/hrt.44.6.699.

Abstract

Attention has recently been drawn to the relatively poor prognosis of middle aged patients paced for chronic atrioventricular block when age-linked expectation of life is taken into account, and it has been suggested that this may be the result of underlying coronary artery disease, despite the absence of symptoms to suggest this. It was the purpose of this study to determine the incidence of unsuspected coronary artery disease in middle aged patients presenting with chronic atrioventricular block. Studies were made on a consecutive series of 30 patients aged 45 to 65 (mean age 56 years) with chronic atrioventricular disease who had been referred for pacing. Patients presenting with acute myocardial infarction or angina or with sinuatrial disease without atrioventricular disease were excluded. Coronary arteriography disclosed the presence of severe coronary artery disease in 13 patients. Of the remaining 17 patients, four had congestive cardiomyopathy, two had hypertrophic cardiomyopathy, one had aortic stenosis, and in 10 patients the aetiology of the heart block was unknown. Myocardial revascularisation was undertaken in six patients with paroxysmal atrioventricular block caused by coronary artery disease. Operation did not result in any sustained improvement in atrioventricular conduction.

摘要

最近,当考虑到与年龄相关的预期寿命时,人们开始关注中年慢性房室传导阻滞患者相对较差的预后,并且有人提出,尽管没有症状提示,但这可能是潜在冠状动脉疾病的结果。本研究的目的是确定患有慢性房室传导阻滞的中年患者中未被怀疑的冠状动脉疾病的发生率。对连续30例年龄在45至65岁(平均年龄56岁)患有慢性房室疾病并被转诊进行起搏治疗的患者进行了研究。排除患有急性心肌梗死或心绞痛或患有无房室疾病的窦房疾病的患者。冠状动脉造影显示13例患者存在严重冠状动脉疾病。在其余17例患者中,4例患有充血性心肌病,2例患有肥厚性心肌病,1例患有主动脉瓣狭窄,10例患者心脏传导阻滞的病因不明。对6例由冠状动脉疾病引起的阵发性房室传导阻滞患者进行了心肌血运重建。手术并未导致房室传导有任何持续改善。

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