Husemeyer R P, Crawley J C
Br J Obstet Gynaecol. 1979 Jun;86(6):426-31. doi: 10.1111/j.1471-0528.1979.tb10784.x.
A method of determining placental intervillous blood flow (IBF) using an inhaled 133Xe technique is described. The method was used to investigate the effect on IBF of epidural analgesia with an initial dose of 37.5 mg bupivacaine. There was no statistically significant reduction in IBF following the initial dose of bupivacaine in spite of a small but statistically significant reduction in mean blood pressure. There was no significant correlation between the change in mean blood pressure and the percentage change in IBF following epidural block although the single largest percentage reduction in IBF was associated with the largest fall in mean blood pressure.
本文描述了一种使用吸入式133Xe技术测定胎盘绒毛间隙血流量（IBF）的方法。该方法用于研究初始剂量为37.5mg布比卡因的硬膜外镇痛对IBF的影响。尽管平均血压有小幅但具有统计学意义的降低，但在给予初始剂量布比卡因后，IBF并无统计学意义上的显著降低。硬膜外阻滞术后，平均血压变化与IBF百分比变化之间无显著相关性，尽管IBF的最大单一百分比降低与平均血压的最大降幅相关。
