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[肾毒性肾炎大鼠肾脏及其他器官实质细胞核中3H-胸腺嘧啶核苷掺入的组织放射自显影研究]

[Histoautoradiographic study of thymidine-3H incorporation into the parenchymal nuclei of the kidneys and other organs in rats with nephrotoxic nephritis].

作者信息

Samoĭlova Z T, Stepanova E N

出版信息

Biull Eksp Biol Med. 1979 Jun;87(6):612-4.

PMID:465701
Abstract

The features of changes in the index of thymidine-3H incorporation into the renal parenchyma in nephrotoxic nephritis are compared to other organs. In the kidneys the index of incorporation inthe epithelial cells of the renal cortex was 7.5-fold and in the brain cortex epithelium 15-fold as increased, respectively. The number of labeled glomerular cells was 2.5-fold as increased. In glomerulonephritis, the index of thymidine-3H incorporation in the epithelium of the adrenals, liver, goiter gland and small intestine lowered within 30-80% from normal.

摘要

将肾毒性肾炎中3H-胸腺嘧啶核苷掺入肾实质的指标变化特征与其他器官进行了比较。在肾脏中,肾皮质上皮细胞的掺入指标分别增加了7.5倍,大脑皮质上皮细胞增加了15倍。标记的肾小球细胞数量增加了2.5倍。在肾小球肾炎中,肾上腺、肝脏、甲状腺和小肠上皮中3H-胸腺嘧啶核苷的掺入指标比正常水平降低了30%-80%。

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