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氚标记胸腺嘧啶核苷在大鼠增殖性肾小球肾炎中肾小球细胞的摄取情况

Tritiated thymidine uptake by glomerular cells in proliferative glomerulonephritis of the rat.

作者信息

Boss J H, Rosenmann E

出版信息

Pathol Eur. 1976;11(2):151-5.

PMID:958733
Abstract

A small but significant number of tritiated thymidine labelled cells were found, by autoradiography, in the glomeruli of rats with Masugi nephritis or chronic serum sickness nephritis. There were no labelled glomerular cells in sections of untreated animals. The findings favour the contention that in proliferative glomerulonephritis, glomerular hypercellularity is due to infiltration of monocytic cells into the tufts where they divide.

摘要

通过放射自显影法发现,在患有马苏吉肾炎或慢性血清病肾炎的大鼠肾小球中存在少量但数量可观的氚标记胸腺嘧啶核苷标记细胞。未处理动物的切片中没有标记的肾小球细胞。这些发现支持了这样一种观点,即在增殖性肾小球肾炎中,肾小球细胞增多是由于单核细胞浸润到肾小球丛中并在其中分裂所致。

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