Eremina S A, Kondrukh T V, Morozova R F, Rogacheva E A
Biull Eksp Biol Med. 1979 Jul;88(7):18-20.
The adrenal cortex of dogs shows a drop in the glucocorticoid content 10--15 sec after the pain action in the presence of the free cholesterol level increase and its esterified form drop. The concentrations of hormones in the blood falls chiefly at the expense of protein bound hydrocortisone. The subsequent phase of the reaction (after 30--60 sec) is characterized by a considerable accumulation of the hormones by the gland. The level of free glucocorticoids significantly increases, the initial ratio of hydrocortisone and cortisone restores, and transcortin depot is filled up. The role of the adrenal and transcortine depot in realization of feedback mechanisms under stress is discussed.
在游离胆固醇水平升高而其酯化形式下降的情况下，疼痛刺激后10 - 15秒，犬的肾上腺皮质糖皮质激素含量下降。血液中激素浓度的降低主要是以蛋白结合氢化可的松为代价。反应的后续阶段（30 - 60秒后）的特征是腺体中激素大量蓄积。游离糖皮质激素水平显著升高，氢化可的松和可的松的初始比例恢复，皮质素储存库得到补充。文中讨论了肾上腺和皮质素储存库在应激状态下反馈机制实现中的作用。
