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[胆固醇给药对严重应激状态下肾上腺皮质的影响]

[Effect of cholesterol administration on the state of the adrenal cortex in severe stress].

作者信息

Ryzhavskiĭ B Ia, Lutsenko M T

出版信息

Biull Eksp Biol Med. 1978 May;85(5):525-8.

PMID:656596
Abstract

The two weeks' effect of cholesterol on the rat adrenal cortex response under conditions of a severe stress was studied. In comparison with control, the degree of the gland activation and its alteration was found to decrease. It is suggested that the effect of cholesterol depends upon the action on the hypothalamus, and upon the adrenocortical tissue as well. The action of cholesterol on the adrenocortical tissue is bound with the cholesterol capacity to retard peroxydation reactions.

摘要

研究了胆固醇在严重应激条件下对大鼠肾上腺皮质反应的两周效应。与对照组相比,发现腺体激活程度及其变化有所降低。提示胆固醇的作用既取决于对下丘脑的作用,也取决于对肾上腺皮质组织的作用。胆固醇对肾上腺皮质组织的作用与胆固醇抑制过氧化反应的能力有关。

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Biull Eksp Biol Med. 1978 May;85(5):525-8.
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