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阴茎原发性恶性黑色素瘤。两例报告并文献复习。

Primary malignant melanoma of the penis. Two cases and a review of the literature.

作者信息

Khezri A A, Dounis A, Roberts J B

出版信息

Br J Urol. 1979 Apr;51(2):147-50. doi: 10.1111/j.1464-410x.1979.tb02850.x.

DOI:10.1111/j.1464-410x.1979.tb02850.x
PMID:465973
Abstract

Two cases of primary malignant melanoma of the penis are reported and 35 cases from the world literature are reviewed. The tumour most commonly started in the glans penis and less frequently from the prepuce. The microscopic appearances were identical with those of tumours arising elsewhere in the skin. A comparison is made between the incidence of melanoma of the penis and melanoma occurring elsewhere on the body surface. Evaluation of the best treatment was difficult because the total number of cases was small and the methods of treatment and results so variable. It would seem that the prognosis of malignant melanoma of the penis is generally poor, although there are sufficient examples of long-term survival after total amputation in Stage I disease to suggest that this radical treatment is justified.

摘要

本文报告了2例阴茎原发性恶性黑色素瘤病例,并对世界文献中的35例病例进行了回顾。肿瘤最常见于阴茎头,较少起源于包皮。显微镜下表现与皮肤其他部位发生的肿瘤相同。对阴茎黑色素瘤与身体其他体表部位黑色素瘤的发病率进行了比较。由于病例总数较少,治疗方法和结果差异很大,因此难以评估最佳治疗方法。阴茎恶性黑色素瘤的预后似乎普遍较差,尽管有足够的I期疾病患者在全阴茎切除术后长期存活的例子,表明这种根治性治疗是合理的。

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引用本文的文献

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Hepatic Metastasis Revealing a Melanoma of the Penis: Case Report.肝转移揭示阴茎黑色素瘤:病例报告
JMIR Dermatol. 2022 Sep 27;5(3):e37400. doi: 10.2196/37400.
2
Malignant melanoma of prepuce: case report.阴茎头恶性黑色素瘤:病例报告
Genitourin Med. 1986 Dec;62(6):399-401. doi: 10.1136/sti.62.6.399.
3
Rare variants of malignant melanoma.恶性黑色素瘤的罕见变体
World J Surg. 1992 Mar-Apr;16(2):173-8. doi: 10.1007/BF02071517.