Spread of steroid-containing foam after intrarectal administration.
作者信息
Hay D J, Sharma H, Irving M H
出版信息
Br Med J. 1979 Jun 30;1(6180):1751-3. doi: 10.1136/bmj.1.6180.1751.
Abstract
The spread of a steroid-containing foam from the rectum was studied in eight normal controls and eight patients with ulcerative colitis proved by biopsy. A standard dose of foam was labelled with technetium-99m adsorbed on to microspheres of Amberlite resin. Immediately after the foam was administered the extent of spread varied considerably, though in no instance did it extend beyond the rectosigmoid. Further scans at 120 and 240 minutes showed no further spread. It is concluded that a steroid-containing foam has a topical effect only on the rectal mucosa.
摘要
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本文引用的文献
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Adjunctive use of a steroid rectal foam in the treatment of ulcerative colitis.
Dis Colon Rectum. 1973 Mar-Apr;16(2):149-51. doi: 10.1007/BF02589932.
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A local foam aerosol in ulcerative colitis.
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