Bourne M S, Flindt M L, Walker J M
Br Med J. 1979 Jul 7;2(6181):10-2. doi: 10.1136/bmj.2.6181.10.
Seven brewery workers developed asthmatic symptoms after using chloramine (chloramine-T) powder as a sterilising agent. They gave positive weal and flare reactions to skin-prick tests with solutions of chloramine at strengths that caused no reactions in unexposed controls. The symptoms did not recur once the men had been removed from areas in which chloramine was handled. As well as causing irritant effects, inhaling dry or liquid aerosols of chloramine may cause sensitisation, with workers being prone to allergic asthma on reexposure. In view of this, measures should be taken to ensure that chloramine is not inhaled.
七名啤酒厂工人在使用氯胺(氯胺 - T)粉末作为消毒剂后出现了哮喘症状。他们对不同浓度氯胺溶液进行皮肤点刺试验时出现了阳性风团和红晕反应,而相同浓度的氯胺溶液在未接触过的对照者身上并未引起反应。一旦这些工人被调离接触氯胺的区域,症状就不再复发。除了产生刺激作用外,吸入氯胺的干燥或液体气雾剂可能会导致致敏,工人再次接触时容易引发过敏性哮喘。鉴于此,应采取措施确保不吸入氯胺。