Lidsky T I, Labuszewski T, Avitable M J, Robinson J H
Brain Res Bull. 1979 Jan-Feb;4(1):9-14. doi: 10.1016/0361-9230(79)90051-0.
This investigation assessed the influences of trigeminal primary sensory afferents upon caudate neuronal activity in locally anesthetized and chloralose anesthetized cats. Afferents from jaw elevator stretch receptors were stimulated via electrodes in the trigeminal mesencephalic nucleus (Mes 5). Afferents from dental and periodontal receptors were stimulated via electrodes in the inferior dental nerve (IDN). Low intensity electrical stimulation of either locus evoked caudate neuronal responses with Mes 5 being more effective. Higher intensity stimulation of IDN in chloralose anesthetized cats was used to determine if thresholds of trigeminal evoked caudate responses corresponded to thresholds of particular fiber groups in the sensory afferent. In all tested units, neuronal responses were only evoked when stimulation was suprathreshold for both A beta and A delta fibers. These data were discussed in relation to processing of oropharyngeal sensory information within the basal ganglia. Possible implications for bucco-lingual dyskinesias were noted.
本研究评估了三叉神经初级感觉传入纤维对局部麻醉和水合氯醛麻醉猫尾状核神经元活动的影响。通过三叉神经中脑核（Mes 5）中的电极刺激来自咬肌牵张感受器的传入纤维。通过下牙槽神经（IDN）中的电极刺激来自牙齿和牙周感受器的传入纤维。对任一部位进行低强度电刺激均可诱发尾状核神经元反应，其中Mes 5更有效。在水合氯醛麻醉的猫中，使用较高强度刺激IDN来确定三叉神经诱发的尾状核反应阈值是否与感觉传入中特定纤维群的阈值相对应。在所有测试单位中，仅当刺激强度超过Aβ和Aδ纤维的阈值时才诱发神经元反应。这些数据结合基底神经节内口咽感觉信息的处理进行了讨论。还指出了对口舌运动障碍的可能影响。
