Hogg N A, Wijdenes J
Cell Tissue Res. 1979 May 18;198(2):295-307. doi: 10.1007/BF00232012.
At hatching, the hermaphrodite duct of Deroceras reticulatum consists of a single cell type designated the Gonadal Stem Cell (GSC). Proliferation of the GSC leads to the formation of numerous ductules each of which forms one of the acini of the gonad. The germinal and supporting cells are derived entirely from the GSC. The germ cells differentiate first, followed by the Sertoli and follicle cells. At the early sperm stage of gonadal development the hermaphrodite duct differentiates to function as a seminal vesicle. Once the GSC are committed to this change they lose their regenerative ability. The only remaining GSC are the cells of the acinar epithelium, and these retain their germinal potential until the death of the animal. Regeneration will occur from the hermaphrodite duct provided it is in the immature state, i.e., composed of GSC, and is exposed to the hormonal conditions of a young animal. Nervous connections and the presence of an artery are not necessary for this regeneration. The presence of a functional gonad does not inhibit regeneration.
在孵化时，网状蛞蝓的雌雄同体管道由一种单一的细胞类型组成，即生殖干细胞（GSC）。生殖干细胞的增殖导致形成许多小导管，每个小导管形成性腺的一个腺泡。生殖细胞和支持细胞完全来源于生殖干细胞。生殖细胞首先分化，随后是支持细胞和卵泡细胞。在性腺发育的早期精子阶段，雌雄同体管道分化为精囊发挥功能。一旦生殖干细胞发生这种变化，它们就会失去再生能力。仅存的生殖干细胞是腺泡上皮细胞，这些细胞在动物死亡前一直保持其生殖潜能。如果雌雄同体管道处于未成熟状态，即由生殖干细胞组成，并暴露于幼龄动物的激素条件下，就会从该管道发生再生。这种再生不需要神经连接和动脉的存在。功能性性腺的存在并不抑制再生。
