入侵红火蚁（Solenopsis invicta Buren）毒液生物碱的抗菌活性
Antibacterial activity of venom alkaloids from the imported fire ant, Solenopsis invicta Buren.
作者信息
Jouvenaz D P, Blum M S, MacCONNELL J G
出版信息
Antimicrob Agents Chemother. 1972 Oct;2(4):291-3. doi: 10.1128/AAC.2.4.291.
Abstract
The antibacterial properties of synthetic fire ant venom alkaloids were tested by disc-diffusion procedures against a variety of bacteria and by doubling concentrations in broth cultures of Staphylococcus aureus and Escherichia coli. Gram-positive bacteria were inhibited by lower concentrations of trans-2-methyl-6-n-undecylpiperidine, trans-2-methyl-6-n-tridecylpiperidine, and trans-2-methyl-6-n-pentadecylpiperidine than were gram-negative bacteria. A fourth alkaloid, trans-2-methyl-6-(cis-6-pentadecenyl)piperidine, which was available in minute quantity and was tested by disc-diffusion only, was ineffective against all organisms.
摘要
通过纸片扩散法对多种细菌测试了合成火蚁毒液生物碱的抗菌特性，并在金黄色葡萄球菌和大肠杆菌的肉汤培养物中采用双倍浓度法进行测试。与革兰氏阴性菌相比，革兰氏阳性菌受反式-2-甲基-6-正十一烷基哌啶、反式-2-甲基-6-正十三烷基哌啶和反式-2-甲基-6-正十五烷基哌啶较低浓度的抑制。第四种生物碱，反式-2-甲基-6-（顺式-6-十五碳烯基）哌啶，因数量极少仅通过纸片扩散法进行了测试，对所有生物体均无效果。
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