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[反复注射皮质类固醇后兔肌腱的生物力学研究]

[Biomechanical studies of rabbit tendons after repeated injections of corticosteroids].

作者信息

Kolev N, Dobrev R

出版信息

Eksp Med Morfol. 1979;18(2):92-7.

PMID:467312
Abstract

The purpose of investigation was to determine and compare the mechanical properties of rabbit tendons, injected with celestone as well as noninjected. The authors accepted the dynamic module during cyclic loading and the damaging tension reduced to an unit of body weight of the rabbit. As a result of the experimental biochemical studies they found that tendons, injected with corticosteroids, presented reduced strength and increased deformity in comparison with the noninjected tendons. Histologic examinations, performed additionaly, revealed that the functional properties of the tendons, injected with corticosteroids, were altered before the occurrence of structural changes in the tendinous tissue.

摘要

本研究的目的是确定并比较注射了倍他米松的兔肌腱和未注射的兔肌腱的力学性能。作者采用了循环加载过程中的动态模量,并将破坏张力换算为兔体重的单位。实验生化研究结果表明,与未注射的肌腱相比,注射了皮质类固醇的肌腱强度降低,畸形增加。另外进行的组织学检查显示,在腱组织出现结构变化之前,注射了皮质类固醇的肌腱的功能特性就已改变。

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