Rindt W
Endokrinologie. 1979 Feb;73(1):27-32.
A combined oral application of 30 micrograms ethinylestradiol with 50 micrograms 17 alpha-ethinyl-18-methyl-11-methylene-4-estren-17-ol (a newly developed progestagen) -- for 21 days resulted in a distinct antigonadotrophic effect, shown by hormone analysis (LH, FSH, estradiol and progesterone) in serum samples of three healthy and fertile women. A final recommendation on the daily dosage, however, depends on the results of clinical experimental investigation still in progress.
将30微克乙炔雌二醇与50微克17α-乙炔基-18-甲基-11-亚甲基-4-雌甾烯-17-醇(一种新开发的孕激素)联合口服21天,在三名健康且有生育能力的女性血清样本中进行的激素分析(LH、FSH、雌二醇和孕酮)显示出明显的抗促性腺激素作用。然而,关于每日剂量的最终建议取决于仍在进行的临床实验研究结果。