[Analysis of afferent impulsation and muscle potentials of the small intestine in response to sucrose].

Changes of potentials in the longitudinal and circular muscles of the small intestine and impulse frequency in mesenteric afferent fibers during intraluminal administration of sucrose solution were studied in cats before and after effects of adreno- and cholinolytic agents. Reserpine, dihydroergotamine, and N-cholinoblocking agents (hexonium or benzohexonium) increased the excitatory effect of sucrose whereas atropine abolished the effect. Atropine in combination with dihydroergotamine did not abolish the activating effect of sucrose. The latter seems to be unrelated to stimulation of either cholinergic or adrenergic intramural neurons. Involvement of substance P is suggested.