[Reception of sucrose in the small intestine after monoamine oxidase and beta-adrenoreceptor block].

In anesthetized cats, potentials of longitudinal muscles of the middle small intestine and impulses of afferent fibers of mesenteric nerves were recorded. Effects of 1-M sucrose solution prior to and after i.v. administration of the MAO blockers and obsidan (beta-adrenoceptor blocker) were compared. After simultaneous blockade of the MAO and the beta-adrenoreceptors, the duration of excitatory effect on smooth muscles induced by intraluminal sucrose administration increased. The pulse rate of mesenteric nerves, with a declining initial background observed as a result of the MAO and the beta-adrenoreceptor blockers action, increased within 25 min after sucrose administration. A hypothesis of the involvement of serotonin of the small intestine mucose entero-chromaffin cells in the primary perception of sugars, is suggested.