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小龙虾巨型中间神经元的连接模式:用钴染料可视化突触区域

Connectivity patterns of crayfish giant interneurons: visualization of synaptic regions with cobalt dye.

作者信息

Mittenthal J E, Wine J J

出版信息

Science. 1973 Jan 12;179(4069):182-4. doi: 10.1126/science.179.4069.182.

DOI:10.1126/science.179.4069.182
PMID:4682249
Abstract

Intracellular injection of cobalt dye was used to visualize electrical synapses between two pairs of central giant interneurons and giant motoneurons in the crayfish central nervous system. A pair of giant motoneurons in each ganglion contacts the interneurons, but not all contact points are functional synapses. Cobalt dye reveals numerous fine projections that are present at synaptic contact points and absent at nonsynaptic contacts; intracellular recording confirms this correlation. The different connectivity patterns of the two pairs of interneurons are consistent with the different behavior patterns which they evoke.

摘要

通过向细胞内注射钴染料来观察小龙虾中枢神经系统中两对中枢巨中间神经元和巨运动神经元之间的电突触。每个神经节中的一对巨运动神经元与中间神经元相接触,但并非所有接触点都是功能性突触。钴染料揭示了在突触接触点处存在而在非突触接触处不存在的许多细微突起;细胞内记录证实了这种相关性。这两对中间神经元不同的连接模式与它们所引发的不同行为模式是一致的。

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