造血干细胞在体外的持久性。
The persistence of hemopoietic stem cells in vitro.
作者信息
Meints R, Goldwasser E
出版信息
J Cell Biol. 1973 Feb;56(2):429-33. doi: 10.1083/jcb.56.2.429.
Abstract
Cells capable of forming colonies in spleens of irradiated mice (CFU) are lost temporarily when bone marrow cells from rats or mice are maintained in culture. Rat marrow CFU go through a minimum at about 3 days after which there is a slow increase in the number of CFU in culture, reaching a maximum at 9 days. Mouse marrow CFU reach a minimum at 3 days and a maximum at 7 days. Some rat marrow CFU persist in culture for as long as 28 days.
摘要
当将大鼠或小鼠的骨髓细胞进行培养时，能够在受辐照小鼠脾脏中形成集落的细胞（CFU）会暂时消失。大鼠骨髓CFU在大约3天时达到最低水平，此后培养物中CFU数量缓慢增加，在9天时达到最高值。小鼠骨髓CFU在3天时达到最低水平，在7天时达到最高值。一些大鼠骨髓CFU在培养中可持续长达28天。
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