Starostin V I, Ianushevskaia M I, Domaratskaia E I
Izv Akad Nauk Ser Biol. 1997 Jan-Feb(1):100-2.
The capacity of CFU-S-11, which formed colonies in the spleen on day 11 after transplantation to an irradiated recipient for self-maintenance, was studied. The indices for self-renewal of individual CFU-S from the spleen, bone marrow, and peripheral blood were compared in the same sexually mature donor mice by retransplanting the colonies isolated from the spleen parenchyma to secondary recipients. The number of secondary CFU-S-11 per primary CFU-S-11 originating from the liver hardly differed from that originating from the peripheral blood, but is almost twice less than for the bone marrow CFU-S-11. The conclusion was drawn that compartment CFU-S of the liver of adult animals contains the cells migrating from blood flow, which, apparently, are not dormant embryonic cells.
研究了CFU-S-11的能力，它在移植到受照射受体后的第11天在脾脏中形成集落以进行自我维持。通过将从脾实质分离的集落重新移植到二级受体中，比较了来自相同性成熟供体小鼠的脾脏、骨髓和外周血中单个CFU-S的自我更新指标。源自肝脏的每个初级CFU-S-11的二级CFU-S-11数量与源自外周血的数量几乎没有差异，但几乎比骨髓CFU-S-11少一半。得出的结论是，成年动物肝脏的CFU-S区室包含从血流迁移而来的细胞，这些细胞显然不是休眠的胚胎细胞。
