针对两种髓磷脂蛋白的抗体之间的相互作用。
The interaction of antibodies to two myelin proteins.
作者信息
Wood D D, Orange R P, Moscarello M A
出版信息
Immunol Commun. 1975;4(1):17-27. doi: 10.3109/08820137509055758.
PMID:46838
Abstract
Antibody has been prepared to a hydrophobic myelin protein in rabbits using several different adjuvants. This antibody was found to react with the myelin basic protein. This latter activity could be absorbed out with basic protein leaving the reactivity to the hydrophobic protein, suggesting that the two myelin proteins shared a common antigenic determinant. In addition, the hydrophobic protein appears to possess a unique antigenic determinant.
摘要
已使用几种不同的佐剂在兔体内制备了针对一种疏水性髓磷脂蛋白的抗体。发现该抗体与髓磷脂碱性蛋白发生反应。后一种活性可以被碱性蛋白吸收掉，而保留对疏水性蛋白的反应性，这表明这两种髓磷脂蛋白共享一个共同的抗原决定簇。此外，疏水性蛋白似乎拥有一个独特的抗原决定簇。
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