髓鞘形成抑制因子：与实验性变应性脑脊髓炎诱导的解离
Myelination inhibition factor: dissociation from induction of experimental allergic encephalomyelitis.
作者信息
Kies M W, Driscoll B F, Seil F J, Alvord E C
出版信息
Science. 1973 Feb 16;179(4074):689-90. doi: 10.1126/science.179.4074.689.
PMID:4119452
Abstract
Sensitization of guinea pigs with purified myelin basic protein induces experimental allergic encephalomyelitis (EAE) but does not induce a serum factor which inhibits myelin formation in vitro. This factor, induced by some unidentified constituent of whole central nervous system tissue, should not be characterized as a component of "EAE serum."
摘要
用纯化的髓鞘碱性蛋白使豚鼠致敏可诱发实验性变应性脑脊髓炎（EAE），但不会诱导产生一种在体外抑制髓鞘形成的血清因子。这种由整个中枢神经系统组织中某些不明成分诱导产生的因子，不应被视为“EAE血清”的一个成分。
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