抗枯草杆菌蛋白酶消化破伤风毒素抗体的毒素中和作用
Toxin-neutralizing effect of antibody against subtilisin-digested tetanus toxin.
作者信息
Sato H, Ito A, Yamakawa Y, Murata R
出版信息
Infect Immun. 1979 Jun;24(3):958-61. doi: 10.1128/iai.24.3.958-961.1979.
Abstract
A form of systemic tetanus with atypical symptoms was observed in mice injected in the left thigh with a mixture of tetanus toxin and antibody produced in guinea pigs against a fragment of toxin obtained from a subtilisin digest of the crystallized toxin. The mice did not show typical symptoms of the local tetanus such as convulsions or spastic paralysis of the injected limb.
摘要
在左大腿注射破伤风毒素与豚鼠产生的针对结晶毒素枯草杆菌蛋白酶消化片段的抗体混合物的小鼠中，观察到一种具有非典型症状的全身性破伤风形式。这些小鼠未表现出局部破伤风的典型症状，如注射肢体的抽搐或痉挛性麻痹。
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