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Toxicity of papain-digested tetanus toxin. Pathological effect of fragment B in the absence of spastic paralysis.

作者信息

Helting T B, Ronneberger H J, Vollerthun R, Neubauer V

出版信息

J Biol Chem. 1978 Jan 10;253(1):125-9.

PMID:563395
Abstract
摘要

相似文献

1
Toxicity of papain-digested tetanus toxin. Pathological effect of fragment B in the absence of spastic paralysis.木瓜蛋白酶消化的破伤风毒素的毒性。片段B在无痉挛性麻痹情况下的病理效应。
J Biol Chem. 1978 Jan 10;253(1):125-9.
2
Enzymatic breakdown of tetanus toxin.破伤风毒素的酶解
Biochem Biophys Res Commun. 1974 Apr 23;57(4):1263-70. doi: 10.1016/0006-291x(74)90832-8.
3
Analysis of the immune response to papain digestion products of tetanus toxin.破伤风毒素木瓜蛋白酶消化产物的免疫反应分析。
Acta Pathol Microbiol Immunol Scand C. 1984 Feb;92(1):59-63. doi: 10.1111/j.1699-0463.1984.tb00052.x.
4
Isolation and purification by high performance liquid chromatography of a tetanus toxin fragment (fragment [A-B]) derived from mildly papain-treated toxin.通过高效液相色谱法对轻度木瓜蛋白酶处理的破伤风毒素衍生的破伤风毒素片段（片段[A - B]）进行分离和纯化。
Toxicon. 1989;27(9):1055-7. doi: 10.1016/0041-0101(89)90157-8.
5
Structure of tetanus toxin. I. Breakdown of the toxin molecule and discrimination between polypeptide fragments.破伤风毒素的结构。I. 毒素分子的分解及多肽片段的鉴别。
J Biol Chem. 1977 Jan 10;252(1):187-93.
6
Toxin-neutralizing effect of antibody against subtilisin-digested tetanus toxin.抗枯草杆菌蛋白酶消化破伤风毒素抗体的毒素中和作用
Infect Immun. 1979 Jun;24(3):958-61. doi: 10.1128/iai.24.3.958-961.1979.
7
The use of antibody Fab fragments specifically directed to two different complementary parts of the tetanus toxin molecule for studying the mode of action of the toxin.
Brain Res. 1985 May 13;334(1):139-46. doi: 10.1016/0006-8993(85)90575-x.
8
Papain-derived fragment IIc of tetanus toxin: its binding to isolated synaptic membranes and retrograde axonal transport.
Brain Res. 1981 Apr 6;210(1-2):291-9. doi: 10.1016/0006-8993(81)90902-1.
9
Chains and fragments of tetanus toxin. Separation, reassociation and pharmacological properties.破伤风毒素的链和片段。分离、重结合及药理学特性。
Eur J Biochem. 1989 Jul 1;182(3):649-56. doi: 10.1111/j.1432-1033.1989.tb14874.x.
10
Relation of spastic and flaccid paralysis to retrograde transport of 125I-tetanus toxin and its 125I-Ibc fragment. Modulating effect of F (ab) antibodies directed to specific areas on the toxin molecule.
Boll Ist Sieroter Milan. 1985;64(1):35-41.

引用本文的文献

1
Monoclonal antibodies as probes of tetanus toxin structure and function.单克隆抗体作为破伤风毒素结构与功能的探针
Infect Immun. 1983 Dec;42(3):942-8. doi: 10.1128/iai.42.3.942-948.1983.
2
Bacterial toxins: cellular mechanisms of action.细菌毒素：细胞作用机制
Microbiol Rev. 1984 Sep;48(3):199-221. doi: 10.1128/mr.48.3.199-221.1984.
3
Cloning, nucleotide sequencing, and expression of tetanus toxin fragment C in Escherichia coli.破伤风毒素C片段在大肠杆菌中的克隆、核苷酸测序及表达
J Bacteriol. 1986 Jan;165(1):21-7. doi: 10.1128/jb.165.1.21-27.1986.
4
Selective inhibition of cytokine-induced lysozyme activity by tetanus toxin in the GG2EE macrophage cell line.破伤风毒素对GG2EE巨噬细胞系中细胞因子诱导的溶菌酶活性的选择性抑制作用
Infect Immun. 1989 Aug;57(8):2452-6. doi: 10.1128/iai.57.8.2452-2456.1989.
5
Isolation, purification, and characterization of fragment B, the NH2-terminal half of the heavy chain of tetanus toxin.破伤风毒素重链氨基末端一半B片段的分离、纯化及特性鉴定
Infect Immun. 1989 Nov;57(11):3588-93. doi: 10.1128/iai.57.11.3588-3593.1989.
6
Toxin-neutralizing effect of antibody against subtilisin-digested tetanus toxin.抗枯草杆菌蛋白酶消化破伤风毒素抗体的毒素中和作用
Infect Immun. 1979 Jun;24(3):958-61. doi: 10.1128/iai.24.3.958-961.1979.
7
Tetanus toxin.破伤风毒素
Microbiol Rev. 1979 Jun;43(2):224-40. doi: 10.1128/mr.43.2.224-240.1979.
8
Enzymatic fragmentation of tetanus toxin. Identification and characterization of an atoxic, immunogenic fragment.破伤风毒素的酶促片段化。一种无毒免疫原性片段的鉴定与表征。
Mol Cell Biochem. 1978 Oct 13;21(1):23-31. doi: 10.1007/BF00230193.