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单针系统(双头泵)上毛细管流动透析器性能的体外比较

An in vitro comparison of capillary flow dialyzer performances on a single needle system (double headpump).

作者信息

Ringoir S, Piron M

出版信息

Int J Artif Organs. 1979 May;2(3):125-31.

PMID:468404
Abstract

The ultrafiltration, clearance and priming characteristics of six capillary dialyzers (C-DAK 2.5 D, C-DAK 1.8 D, Tri-Ex 1, CF M 1500, N16F160 and HF 150) were studied in single needle dialysis by way of the double headpump (BL 760, Bellco Ltd). A good control of the ultrafiltration by an appropriate choice of the mean bloodcompartment pressures (Pbo) is present in all dialyzers. After correction of the clearance for ultrafiltration the clearances of urea, creatinine, sodiumiothalamate-l125 and cyanocobalamine-Co58 (vit. B 12) rise with increasing mean pressures in the bloodcompartment of all dialyzers. We assume that a better use of available surface area due to the characteristics of the double headpump such as TMP mainly influenced by Pbo pressures and other such as tidal flow are responsible for the excellent in vitro clearances of these dialyzers with this type of single needle system.

摘要

采用双头泵(BL 760,Bellco有限公司),通过单针透析研究了六种毛细管透析器(C-DAK 2.5 D、C-DAK 1.8 D、Tri-Ex 1、CF M 1500、N16F160和HF 150)的超滤、清除率和预充特性。通过适当选择平均血液腔压力(Pbo),所有透析器的超滤均可得到良好控制。在对超滤清除率进行校正后,所有透析器血液腔中尿素、肌酐、碘肽酸钠-I125和钴胺素-Co58(维生素B 12)的清除率均随平均压力的升高而升高。我们认为,由于双头泵的特性,如主要受Pbo压力影响的跨膜压(TMP)和其他如潮流动等特性,能更好地利用有效表面积,这是这些透析器在这种单针系统中具有出色体外清除率的原因。

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