用TL细胞群体免疫的小鼠产生TL抗体。胸腺激素的一种可能检测方法。
Production of TL antibody by mice immunized with TL- cell populations. A possible assay for thymic hormone.
作者信息
Komuro K, Boyse E A, Old L J
出版信息
J Exp Med. 1973 Feb 1;137(2):533-6. doi: 10.1084/jem.137.2.533.
Abstract
TL(-) mice make TL antibody when immunized with spleen or bone marrow cells from TL(+) donors, despite the fact that these cells do not express TL antigen. This has been shown to depend on maturation of TL(-) precursors, contained in the inoculum, into TL(+) cells under influence of the recipient's thymus; the differentiated TL(+) cells then evoke production of TL antibody.
摘要
TL(-)小鼠在用来自TL(+)供体的脾细胞或骨髓细胞免疫时会产生TL抗体，尽管这些细胞不表达TL抗原。已证明这取决于接种物中所含的TL(-)前体细胞在受体胸腺的影响下成熟为TL(+)细胞；分化后的TL(+)细胞随后引发TL抗体的产生。
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