Hajji M A, Wilson T A, Lai-Fook S J
J Appl Physiol Respir Environ Exerc Physiol. 1979 Jul;47(1):175-81. doi: 10.1152/jappl.1979.47.1.175.
The continuum solution for the deformation of an elastic half space covered by a membrane is used to interpret measurements of the indentation of lung lobes under a column of fluid. The shear modulus mu of the underlying parenchyma is found to be approximately 0.7 times transpulmonary pressure, independent of species size. The tension in the pleural membrane T increases rapidly with increasing membrane area. For dog lungs, the value of T is 10(3) to 10(4) dyn/cm. For the larger species tested, pigs and horses, T is larger. The continuum solution shows that a concentrated force applied to the pleural surface is distributed over a distance T/mu as it is transmitted across the pleural membrane. The membrane is important in determining the displacement produced by forces that act within a region that is small compared to this distance, approximately 2 cm for dog lungs. By comparing the tension-area curve of the pleural membrane with the pressure-volume curve of the lobe, it is found that the pleural membrane contributes about 20% of the work done by the lung during deflation.
利用弹性半空间覆盖薄膜变形的连续介质解来解释在液柱下肺叶压痕的测量结果。发现下层实质组织的剪切模量μ约为跨肺压的0.7倍，与物种大小无关。胸膜的张力T随膜面积增加而迅速增大。对于犬肺，T的值为10³至10⁴达因/厘米。对于测试的较大物种猪和马，T更大。连续介质解表明，施加于胸膜表面的集中力在穿过胸膜时会在T/μ的距离上分布。对于与该距离相比小的区域（犬肺约为2厘米）内起作用的力，该膜在确定其产生的位移方面很重要。通过比较胸膜的张力 - 面积曲线与肺叶的压力 - 容积曲线，发现胸膜在肺放气过程中所做的功中约占20%。
