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橄榄酸,一类由链霉菌属产生的具有β-内酰胺酶抑制特性的β-内酰胺抗生素。II. 从橄榄色链霉菌中分离和鉴定橄榄酸MM 4550、MM 13902和MM 17880

Olivanic acids, a family of beta-lactam antibiotics with beta-lactamase inhibitory properties produced by Streptomyces species. II. Isolation and characterisation of the olivanic acids MM 4550, MM 13902 and MM 17880 from Streptomyces olivaceus.

作者信息

Hood J D, Box S J, Verrall M S

出版信息

J Antibiot (Tokyo). 1979 Apr;32(4):295-304. doi: 10.7164/antibiotics.32.295.

DOI:10.7164/antibiotics.32.295
PMID:468716
Abstract

The olivanic acids MM 4550, MM 13902 and MM 17880 are members of a new family of beta-lactam antibiotics. An isolation and purification process utilising ion-par extraction and ion-exchange chromatography is described and the metabolites are characterised by physico-chemical and biological properties.

摘要

橄榄酸MM 4550、MM 13902和MM 17880是一类新型β-内酰胺抗生素家族的成员。本文描述了一种利用离子对萃取和离子交换色谱法的分离纯化工艺,并通过物理化学和生物学特性对这些代谢产物进行了表征。

相似文献

1
Olivanic acids, a family of beta-lactam antibiotics with beta-lactamase inhibitory properties produced by Streptomyces species. II. Isolation and characterisation of the olivanic acids MM 4550, MM 13902 and MM 17880 from Streptomyces olivaceus.橄榄酸,一类由链霉菌属产生的具有β-内酰胺酶抑制特性的β-内酰胺抗生素。II. 从橄榄色链霉菌中分离和鉴定橄榄酸MM 4550、MM 13902和MM 17880
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Four further antibiotics related to olivanic acid produced by Streptomyces olivaceus: fermentation, isolation, characterisation and biosynthetic studies.由橄榄链霉菌产生的与橄榄酸相关的另外四种抗生素:发酵、分离、表征及生物合成研究
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Olivanic acids, a family of beta-lactam antibiotics with beta-lactamase inhibitory properties produced by Streptomyces species. I. Detection, properties and fermentation studies.橄榄酸,一类由链霉菌属产生的具有β-内酰胺酶抑制特性的β-内酰胺抗生素。I. 检测、特性及发酵研究。
J Antibiot (Tokyo). 1979 Apr;32(4):287-94. doi: 10.7164/antibiotics.32.287.
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PS-6 and PS-7, new beta-lactam antibiotics. Isolation, physicochemical properties and structures.PS - 6和PS - 7,新型β - 内酰胺抗生素。分离、理化性质及结构
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A new olivanic acid derivative produced by Streptomyces olivaceus: isolation and structural studies.
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Comparative antibacterial properties in vitro of seven olivanic acid derivatives: MM 4550, MM 13902, MM 17880, MM 22380, MM 22381, MM 22382 and MM 22383.七种橄榄酸衍生物MM 4550、MM 13902、MM 17880、MM 22380、MM 22381、MM 22382和MM 22383的体外抗菌性能比较
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Asparenomycin A, a new carbapenem antibiotic.阿丝帕霉素A,一种新型碳青霉烯类抗生素。
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Structures of olivanic acid derivatives MM 22380, MM 22381, MM 22382 and MM 22383; four new antibiotics isolated from Streptomyces olivaceus.橄榄酸衍生物MM 22380、MM 22381、MM 22382和MM 22383的结构;从橄榄色链霉菌中分离出的四种新型抗生素。
J Antibiot (Tokyo). 1979 Sep;32(9):961-3. doi: 10.7164/antibiotics.32.961.

引用本文的文献

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Identification and characterization of the carbapenem MM 4550 and its gene cluster in Streptomyces argenteolus ATCC 11009.从链霉菌属 ATCC 11009 中鉴定和表征碳青霉烯 MM 4550 及其基因簇。
Chembiochem. 2014 Jan 24;15(2):320-31. doi: 10.1002/cbic.201300319. Epub 2014 Jan 13.
2
Antimicrobial and beta-lactamase inhibitory activities of carpetimycins A and B, new carbapenem antibiotics.新型碳青霉烯类抗生素卡培霉素A和B的抗菌及β-内酰胺酶抑制活性
Antimicrob Agents Chemother. 1982 Apr;21(4):536-44. doi: 10.1128/AAC.21.4.536.
3
In vitro and pharmacokinetic properties of the carbapenems.
碳青霉烯类药物的体外及药代动力学特性。
Antimicrob Agents Chemother. 1986 Sep;30(3):343-9. doi: 10.1128/AAC.30.3.343.
4
Inhibition of the beta-lactamases of Branhamella catarrhalis by clavulanic acid and other inhibitors.棒酸及其他抑制剂对卡他莫拉菌β-内酰胺酶的抑制作用。
Drugs. 1986;31 Suppl 3:70-8. doi: 10.2165/00003495-198600313-00015.
5
Beta-lactamase inhibitors from laboratory to clinic.从实验室到临床的β-内酰胺酶抑制剂
Clin Microbiol Rev. 1988 Jan;1(1):109-23. doi: 10.1128/CMR.1.1.109.