Matter A
J Cell Biol. 1973 Mar;56(3):690-6. doi: 10.1083/jcb.56.3.690.
A morphometric study of the nexus of rat cardiac muscle was carried out. The nexus surface of one intercalated disk of one 15 microm thick fiber is found to range between 47 microm(2) and 94 microm(2), the latter value taking into account the maximal underestimation caused by tangential sectioning. Dividing the lower, minimal value by the surface of the observed subunits (90 A periodicity), one obtains for one intercalated disk 6.7 x 10(5) subunits, each of them assumed to be permeated by a central pore. These pores are thought to be equivalent to intercellular channels in a recently proposed model. Taking our morphometric and recently reported physiological values, this model is examined for its consistency with a low resistance pathway between cardiac muscle cells.
对大鼠心肌连接进行了形态测量学研究。发现一根15微米厚纤维的一个闰盘的连接表面在47平方微米至94平方微米之间，后者是考虑到切线切片造成的最大低估后的值。用较低的最小值除以观察到的亚基表面（90埃周期性），一个闰盘可得到6.7×10⁵个亚基，假定每个亚基都有一个中央孔贯穿。在最近提出的一个模型中，这些孔被认为等同于细胞间通道。结合我们的形态测量值和最近报道的生理学值，对该模型与心肌细胞间低电阻通路的一致性进行了检验。
