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抗血小板血清给药后血管内皮与白细胞之间的相互作用增强：在血管缺陷形成中的作用

Increased interaction of vascular endothelium and leucocytes after administration of antiplatelet serum: role in the developing vascular defect.

作者信息

Kovacs I B, Caen J P

出版信息

J Clin Pathol. 1979 May;32(5):445-9. doi: 10.1136/jcp.32.5.445.

DOI:10.1136/jcp.32.5.445
PMID:469002
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1145705/
Abstract

Antiplatelet serum (APS) induced an increase in the stickiness of white cells which manifests itself in the increase in number of granulocytes rolling along or sticking to the venous endothelium. Lidocaine treatment prevented the increased stickiness of white cells and, at the same time, the microvascular haemorrhage developing after APS. It can be assumed that increased stickiness of white cells after APS may contribute to endothelial damage.

摘要

抗血小板血清（APS）可使白细胞黏附性增加，表现为沿静脉内皮滚动或黏附的粒细胞数量增多。利多卡因治疗可防止白细胞黏附性增加，同时也能防止APS后发生的微血管出血。可以推测，APS后白细胞黏附性增加可能会导致内皮损伤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4946/1145705/ce878f835fca/jclinpath00453-0032-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4946/1145705/ce878f835fca/jclinpath00453-0032-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4946/1145705/ce878f835fca/jclinpath00453-0032-a.jpg

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本文引用的文献

1
Morphology and enumeration of human blood platelets.人体血小板的形态学与计数
J Appl Physiol. 1950 Dec;3(6):365-77. doi: 10.1152/jappl.1950.3.6.365.
2
Allergic purpura, including purpura due to foods, drugs and infections.过敏性紫癜，包括食物、药物和感染所致的紫癜。
Am J Med. 1953 May;14(5):605-32. doi: 10.1016/0002-9343(53)90377-5.
3
Current concepts of microcirculatory behavior.微循环行为的当前概念。
Bibl Anat. 1965;7:2-8.
4
In vivo quantitation of local anesthetic suppression of leukocyte adherence.局部麻醉药对白细胞黏附抑制作用的体内定量研究
Am J Pathol. 1972 Aug;68(2):327-38.
5
Venous endothelial damage produced by massive sticking and emigration of leukocytes.白细胞大量黏附与游出所导致的静脉内皮损伤。
Am J Pathol. 1974 Mar;74(3):507-32.
6
Quantitative investigations of the adhesiveness of circulating polymorphonuclear leucocytes to blood vessel walls.循环多形核白细胞与血管壁黏附性的定量研究。
J Physiol. 1972 Apr;222(2):447-74. doi: 10.1113/jphysiol.1972.sp009808.
7
Are platelets important in inflammation?血小板在炎症中重要吗？
Agents Actions. 1975 Feb;5(1):31-4. doi: 10.1007/BF02027155.
8
Ultrastructural changes of endothelium associated with thrombocytopenia.与血小板减少相关的内皮超微结构变化。
Blood. 1975 Oct;46(4):567-78.
9
In vitro granulocyte adherence and in vivo margination: two associated complement-dependent functions. Studies based on the acute neutropenia of filtration leukophoresis.体外粒细胞黏附与体内边缘化：两种相关的补体依赖性功能。基于过滤白细胞去除术所致急性中性粒细胞减少症的研究。
J Exp Med. 1977 Sep 1;146(3):641-52. doi: 10.1084/jem.146.3.641.
10
Influence of local anesthetics upon human polymorphonuclear leukocyte function in vitro. Reduction of lysosomal enzyme release and superoxide anion production.局部麻醉药对人多形核白细胞体外功能的影响。溶酶体酶释放和超氧阴离子产生的减少。
J Exp Med. 1977 Aug 1;146(2):483-94. doi: 10.1084/jem.146.2.483.