Szafran Z, Nowak J, Szafran H, Janik A
J Clin Chem Clin Biochem. 1979 May;17(5):321-4. doi: 10.1515/cclm.1979.17.5.321.
Esterolytic activity of blood serum was determined in infants with hypertrophic pyloric stenosis and in healthy control children. The substrates hydrolyzed mainly by arylesterase (EC. 3.1.1.2), i.e. p-nitrophenyl esters of acetic, propionic and butyric acid were used. It was found that in infants with hypertrophic pyloric stenosis the rate of p-nitrophenyl propionate hydrolysis was significantly higher than that of the acetate or butyrate. In control group children all three substrates were hydrolysed at similar rates, and these were significantly lower than in infants with hypertrophic pyloric stenosis.
测定了肥厚性幽门狭窄婴儿和健康对照儿童血清的酯酶活性。主要使用由芳基酯酶（EC. 3.1.1.2）水解的底物，即乙酸、丙酸和丁酸的对硝基苯酯。结果发现，肥厚性幽门狭窄婴儿中丙酸对硝基苯酯的水解速率显著高于乙酸酯或丁酸酯。在对照组儿童中，所有三种底物的水解速率相似，且显著低于肥厚性幽门狭窄婴儿。
