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急性听力损失患者的病毒学与流行病学研究

A virological and epidemiological study of patients with acute hearing loss.

作者信息

Rowson K E, Hinchcliffe R

出版信息

Lancet. 1975 Mar 1;1(7905):471-3. doi: 10.1016/s0140-6736(75)92826-3.

DOI:10.1016/s0140-6736(75)92826-3
PMID:46953
Abstract

Virological and epidemiological data were examined in thirty-nine patients with acute hearing loss. The hearing loss was unilateral in thirty-one patients and bilateral in eight. There was a history of upper-respiratory-tract infection before onset of deafness in ten of the patients. Cases were more common in the autumn, with nineteen of the cases occurring in the 3 months from September to November. About half of the patients were 20-40 years old and half 46-73 years old; only one patient was aged less than 20 years. Antibodies to several common viruses were titrated, and there was evidence of recent infection by mumps virus in one case and by Mycoplasma pneumoniae in another. Although no evidence of recent virus infection was found in the remaining patients, it is suggested that the condition may be viral in origin and that further studies should be undertaken.

摘要

对39例急性听力丧失患者的病毒学和流行病学数据进行了检查。31例患者听力丧失为单侧,8例为双侧。10例患者在耳聋发作前有上呼吸道感染史。病例在秋季更为常见,其中19例发生在9月至11月的3个月内。约一半患者年龄在20 - 40岁之间,另一半在46 - 73岁之间;只有1例患者年龄小于20岁。对几种常见病毒的抗体进行了滴定,有证据表明1例患者近期感染了腮腺炎病毒,另1例感染了肺炎支原体。尽管在其余患者中未发现近期病毒感染的证据,但提示该病可能起源于病毒,应进一步开展研究。

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