柯萨奇B4病毒感染与糖尿病之间缺乏因果关联。
Lack of causal association between Coxsackie B4 virus infection and diabetes.
作者信息
Dippe S E, Bennett P H, Miller M, Maynard J E, Berquist K R
出版信息
Lancet. 1975 Jun 14;1(7920):1314-7. doi: 10.1016/s0140-6736(75)92318-1.
PMID:49517
Abstract
An epidemic of Coxsackie B4 virus infection in an isolated group of islands in the Bering Sea in 1967 provided an opportunity to test the suggestion that infection with this virus might be associated with an increased incidence of diabetes. In 1973 islanders were tested by glucose-tolerance tests and their two-hour plasma glucose levels were analysed in the light of serological evidence of CB4 infection five years earlier. There was no evidence of any increased prevalence of diabetes in those who had been infected in 1967.
摘要
1967年，白令海一群与世隔绝的岛屿上爆发了柯萨奇B4病毒感染疫情，这为检验该病毒感染可能与糖尿病发病率增加有关这一观点提供了契机。1973年，对岛上居民进行了葡萄糖耐量测试，并根据五年前CB4感染的血清学证据分析了他们两小时的血浆葡萄糖水平。没有证据表明1967年感染病毒的人群中糖尿病患病率有所增加。
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