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A biologically active metabolite of cyclophosphamide.

作者信息

Colvin M, Padgett C A, Fenselau C

出版信息

Cancer Res. 1973 Apr;33(4):915-8.

PMID:4696485
Abstract
摘要

相似文献

1
A biologically active metabolite of cyclophosphamide.环磷酰胺的一种生物活性代谢物。
Cancer Res. 1973 Apr;33(4):915-8.
2
Identification of aldophosphamide as a metabolite of cyclophosphamide in vitro and in vivo in humans.在体外和人体内将醛磷酰胺鉴定为环磷酰胺的一种代谢产物。
Cancer Res. 1977 Aug;37(8 Pt 1):2538-43.
3
Isolation and identification of a stabilized derivative of aldophosphamide, a major metabolite of cyclophosphamide.
Cancer Res. 1974 Nov;34(11):2933-5.
4
Metabolism of iphosphamide (2-(2-chloroethylamino)-3-(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide) and production of a toxic iphosphamide metabolite.
Cancer Res. 1973 May;33(5):1016-22.
5
Isolation and mass spectral identification of blood metabolites of cyclophosphamide: evidence for phosphoramide mustard as the biologically active metabolite.
Biomed Mass Spectrom. 1975 Feb;2(1):46-52. doi: 10.1002/bms.1200020109.
6
Approaches to the pharmacokinetics of cyclophosphamide (NSC 26271): Quantitation of metabolites.
Cancer Treat Rep. 1976 Apr;60(4):403-8.
7
The use of deuterated analogs in qualitative and quantitative investigations of the metabolism of cyclophosphamide (NSC-26271).氘代类似物在环磷酰胺（NSC - 26271）代谢定性和定量研究中的应用
Cancer Treat Rep. 1976 Apr;60(4):483-91.
8
Characterization of the major sheep urinary metabolites of cyclophosphamide, a defleecing chemical.一种脱毛化学品环磷酰胺的主要绵羊尿液代谢产物的表征
J Agric Food Chem. 1971 Jul-Aug;19(4):788-90. doi: 10.1021/jf60176a038.
9
Evidence for an aldehyde possessing alkylating activity as the primary metabolite of cyclophosphamide.有证据表明，一种具有烷基化活性的醛是环磷酰胺的主要代谢产物。
Cancer Res. 1973 Apr;33(4):651-8.
10
[Immunosuppressant effect of cyclophosphamide activated in vitro by liver microsomes from different strains of mice].[不同品系小鼠肝脏微粒体体外激活环磷酰胺的免疫抑制作用]
Biull Eksp Biol Med. 1981 Jul;92(7):57-60.

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Proton magnetic resonance studies of the decomposition of 4-hydroxycyclophosphamide, a microsomal metabolite of cyclophosphamide.
质子磁共振研究 4-羟基环磷酰胺的分解，环磷酰胺的一种微粒体代谢物。
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4
Comparative metabolism of cyclophosphamide and ifosfamide in the mouse using UPLC-ESI-QTOFMS-based metabolomics.基于 UPLC-ESI-QTOFMS 的代谢组学研究在小鼠体内环磷酰胺和异环磷酰胺的比较代谢。
Biochem Pharmacol. 2010 Oct 1;80(7):1063-74. doi: 10.1016/j.bcp.2010.06.002. Epub 2010 Jun 10.
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Curr Cancer Drug Targets. 2008 May;8(3):172-9. doi: 10.2174/156800908784293631.
6
Preclinical pharmacokinetics and stability of isophosphoramide mustard.异环磷酰胺氮芥的临床前药代动力学与稳定性
Cancer Chemother Pharmacol. 1994;33(5):391-8. doi: 10.1007/BF00686268.
7
The pharmacokinetics of cyclophosphamide, phosphoramide mustard and nor-nitrogen mustard studied by gas chromatography in patients receiving cyclophosphamide therapy.采用气相色谱法研究接受环磷酰胺治疗的患者中环磷酰胺、磷酰胺氮芥和去甲氮芥的药代动力学。
Br J Clin Pharmacol. 1980 Oct;10(4):327-35. doi: 10.1111/j.1365-2125.1980.tb01768.x.
8
Chemosensitivity of human neoplasms with in vitro clone formation. Experience at the University of Southern California - Los Angeles County Medical Center.人肿瘤体外克隆形成的化学敏感性。南加州大学 - 洛杉矶县医疗中心的经验。
Cancer Chemother Pharmacol. 1981;6(3):245-51. doi: 10.1007/BF00256977.
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Clinical pharmacokinetics of commonly used anticancer drugs.常用抗癌药物的临床药代动力学
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10
Pharmacokinetics of anticancer drugs in children.儿童抗癌药物的药代动力学
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