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谷氨酸在兔海马CA1区、CA3区及齿状区各层中的分布。

Distribution of glutamate in layers of the rabbit hippocampal fields CA1, CA3, and the dentate area.

作者信息

Nitsch C, Okada Y

出版信息

J Neurosci Res. 1979;4(3):161-7. doi: 10.1002/jnr.490040302.

DOI:10.1002/jnr.490040302
PMID:469955
Abstract

The distribution of L-glutamic acid in single layers dissected from freeze-dried sections of the rabbit hippocampus was estimated by means of an enzymatic cycling procedure. Although the regional variation in glutamate content is less than that of other transmitter candidates, there were present significant differences in it between the projection fields of certain fiber connections. Glutamate concentration was highest in the termination areas of commissural fibers and Schaffer's collaterals.

摘要

通过酶循环法估算了从兔海马冷冻干燥切片中分离出的单层中L-谷氨酸的分布。尽管谷氨酸含量的区域差异小于其他候选递质,但某些纤维连接的投射区域之间存在显著差异。谷氨酸浓度在连合纤维和谢弗侧支的终末区域最高。

相似文献

1
Distribution of glutamate in layers of the rabbit hippocampal fields CA1, CA3, and the dentate area.谷氨酸在兔海马CA1区、CA3区及齿状区各层中的分布。
J Neurosci Res. 1979;4(3):161-7. doi: 10.1002/jnr.490040302.
2
Glutamate as a transmitter of the hippocampal commissural system.谷氨酸作为海马连合系统的一种神经递质。
Adv Biochem Psychopharmacol. 1981;29:97-104.
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Coexistence of GABA and glutamate in mossy fiber terminals of the primate hippocampus: an ultrastructural study.灵长类海马苔藓纤维终末中γ-氨基丁酸(GABA)与谷氨酸的共存:一项超微结构研究
J Comp Neurol. 1991 Jan 8;303(2):177-92. doi: 10.1002/cne.903030202.
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The distribution of glycine, GABA, glutamate and aspartate in rabbit spinal cord, cerebellum and hippocampus.
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[Functional characteristics of connections: Schaffer's collaterals to the CA1 field of the hippocampus in experiments in vivo and in vitro].[连接的功能特性:体内和体外实验中海马体CA1区的谢弗侧支]
Neirofiziologiia. 1979;11(3):208-17.
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Hippocampus as comparator: role of the two input and two output systems of the hippocampus in selection and registration of information.海马体作为比较器:海马体的两个输入和两个输出系统在信息选择与登记中的作用。
Hippocampus. 2001;11(5):578-98. doi: 10.1002/hipo.1073.
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Ultrastructural description of glutamate-, aspartate-, taurine-, and glycine-like immunoreactive terminals from five rat brain regions.来自大鼠五个脑区的谷氨酸、天冬氨酸、牛磺酸和甘氨酸样免疫反应性终末的超微结构描述
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[Cerebral GABA, glutamate, aspartate and transaminases in the insulin nervous syndrome].
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Immunocytochemical localization of GABA-, cholecystokinin-, vasoactive intestinal polypeptide-, and somatostatin-like immunoreactivity in the area dentata and hippocampus of the rat.大鼠齿状回和海马中γ-氨基丁酸、胆囊收缩素、血管活性肠肽和生长抑素样免疫反应性的免疫细胞化学定位
J Comp Neurol. 1987 Feb 1;256(1):42-60. doi: 10.1002/cne.902560105.

引用本文的文献

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Functional changes of glial glutamate transporter GLT-1 during ischemia: an in vivo study in the hippocampal CA1 of normal mice and mutant mice lacking GLT-1.缺血期间胶质细胞谷氨酸转运体GLT-1的功能变化:在正常小鼠和缺乏GLT-1的突变小鼠海马CA1区的体内研究
J Neurosci. 2003 Aug 6;23(18):7176-82. doi: 10.1523/JNEUROSCI.23-18-07176.2003.
2
Neurotoxicity of Clostridium perfringens epsilon-toxin for the rat hippocampus via the glutamatergic system.产气荚膜梭菌ε毒素通过谷氨酸能系统对大鼠海马体的神经毒性作用。
Infect Immun. 1998 Jun;66(6):2501-8. doi: 10.1128/IAI.66.6.2501-2508.1998.