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加利福尼亚某社区新生儿期后不明原因猝死

Post-neonatal sudden unexplained death in a California community.

作者信息

Borhani N O, Rooney P A, Kraus J F

出版信息

Calif Med. 1973 May;118(5):12-6.

Abstract

To gain further insight into the problem of infant sudden death, a study was undertaken to investigate a complete series of cases of infant sudden unexplained death that occurred during a seven-year period in Sacramento County. Needed information was abstracted from autopsy records, Medical Examiner's records and death certificates. The average death rate for the seven-year period was 1.7 for 1,000 live births. Average age at time of death was 2.8 months. There were no records of sudden death among infants over the age of eight months. Higher than average death rates were observed within many of the low socioeconomic areas of Sacramento County. Also, sudden unexplained deaths appeared to occur more frequently in the winter months than in the spring, summer or fall. In over half the cases the infants had a cold, the sniffles, or other respiratory tract congestion within two weeks of the date of death, which seems to support the oft-quoted contention concerning the possibility of nasal obstruction which could initiate the fatal apnea. An additional notable finding was the very frequent occurrence of petechial hemorrhage in the thymus, heart, and lung tissues. The unique age distribution of these deaths in combination with the high frequency of low socioeconomic groups and the frequency of minor respiratory ailment would suggest approaches that can be taken to identify infants at high risk and thus initiate effective community health programs for prevention.

摘要

为了更深入地了解婴儿猝死问题,开展了一项研究,调查萨克拉门托县在七年期间发生的一系列婴儿不明原因猝死病例。所需信息从尸检记录、法医记录和死亡证明中提取。七年期间的平均死亡率为每1000例活产中有1.7例。死亡时的平均年龄为2.8个月。八个月以上婴儿无猝死记录。在萨克拉门托县许多社会经济地位较低的地区,观察到死亡率高于平均水平。此外,不明原因猝死似乎在冬季比在春季、夏季或秋季更频繁发生。在超过一半的病例中,婴儿在死亡日期前两周内患有感冒、鼻塞或其他呼吸道充血,这似乎支持了经常被引用的关于鼻阻塞可能引发致命呼吸暂停的观点。另一个值得注意的发现是,胸腺、心脏和肺组织中经常出现瘀点性出血。这些死亡独特的年龄分布,加上社会经济地位较低群体的高发病率以及轻微呼吸道疾病的高发病率,表明可以采取一些方法来识别高危婴儿,从而启动有效的社区预防健康项目。

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本文引用的文献

2
Sudden, unexpected death in infants. An epidemiologic study.婴儿猝死。一项流行病学研究。
Am J Epidemiol. 1966 Nov;84(3):478-82. doi: 10.1093/oxfordjournals.aje.a120660.
4
Sudden unexpected death in infancy syndrome.婴儿猝死综合征
Am J Dis Child. 1968 Aug;116(2):115-9. doi: 10.1001/archpedi.1968.02100020117001.
9
Sudden death in babies: epidemiology.婴儿猝死:流行病学
Am J Cardiol. 1968 Oct;22(4):457-68. doi: 10.1016/0002-9149(68)90152-5.
10
Discriminatory risk factors in post-neonatal sudden unexplained death.
Am J Epidemiol. 1972 Nov;96(5):328-33. doi: 10.1093/oxfordjournals.aje.a121463.

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