Marcus J, Ehrlich R, Kelly M, Murphy E G
Can Med Assoc J. 1973 May 5;108(9):1116-9.
Sixty-nine diabetic children were studied with respect to the motor nerve conduction velocities, duration of illness and adequacy of control.As a group there was a trend for children with diabetes to have slower MNCV than non-diabetic children, and for the slowing to become progressive as the duration of their disease increased. Poorer quality of diabetes control was also associated with progressive slowing of conduction but the exact relationship is uncertain, since no patient who had diabetes for more than four years was well controlled.Theories of causation of peripheral neuropathy in diabetic patients are reviewed; metabolic changes, rather than other factors, are thought most likely in children.
对69名糖尿病儿童进行了运动神经传导速度、病程和控制情况的研究。总体而言,糖尿病儿童比非糖尿病儿童有运动神经传导速度较慢的趋势,并且随着病程延长,这种减慢会逐渐加重。糖尿病控制质量较差也与传导的逐渐减慢有关,但确切关系尚不确定,因为没有一名糖尿病病程超过四年的患者得到良好控制。本文回顾了糖尿病患者周围神经病变的病因理论;代谢变化而非其他因素被认为最有可能是儿童发病的原因。