Zimmerman T S, Müller-Eberhard H J
Science. 1973 Jun 15;180(4091):1183-5. doi: 10.1126/science.180.4091.1183.
Polypeptides of high molecular weight are deleted from the sedimentable fraction of platelets subjected, while intact, to complement action. These polypeptides, distinct from the previously described thrombin-sensitive protein of this fraction, also diminish after platelets are exposed to thrombin. They may be of importance in the molecular events underlying complement-triggered changes in platelet function.
完整状态下受到补体作用的血小板可沉降部分中,高分子量的多肽被清除。这些多肽与该部分先前描述的凝血酶敏感蛋白不同,在血小板暴露于凝血酶后也会减少。它们可能在补体触发的血小板功能变化的分子事件中具有重要意义。