Pazourek J
Neoplasma. 1979;26(2):201-4.
The special feature of nucleolar morphology which reflects the intensity of ribosomal RNA precursor molecule formation and thus also the intensity of proteosynthesis was studied in contact surface preparations from tissue samples of 28 patients with epithelial tumors of the bladder and in tissue samples of bladder mucosa from 16 patients with prostata hypertrophy (7 of them suffered also from cystolithiasis). In malignant lesions of the bladder mucosa, especially in tumors of medium and high grade malignancy, very low values of metabolically resting cells with ring shaped nucleoli and micronucleoli were found.
在28例膀胱上皮肿瘤患者的组织样本接触表面制剂以及16例前列腺肥大患者的膀胱黏膜组织样本（其中7例还患有膀胱结石）中，研究了核仁形态的特殊特征，该特征反映了核糖体RNA前体分子形成的强度，进而也反映了蛋白质合成的强度。在膀胱黏膜的恶性病变中，尤其是在中高等级恶性肿瘤中，发现代谢静止细胞中具有环形核仁和微核仁的比例非常低。
