双分子脂膜的电击穿作为一种机电不稳定性
Electrical breakdown of bimolecular lipid membranes as an electromechanical instability.
作者信息
Crowley J M
出版信息
Biophys J. 1973 Jul;13(7):711-24. doi: 10.1016/S0006-3495(73)86017-5.
Abstract
The bimolecular lipid membrane (BLM) is modeled as a bulk elastic layer subject to a compressive electric force caused by applied voltages. Analysis of this model shows that a compressive instability develops when the electric stress exceeds a critical value. This instability tends to crush the film and thus rupture it. The predicted breakdown voltage, when compared with measured values for phosphatidylcholine and cholesterol, shows fair agreement, considering the uncertainty in the estimate of elastic parameters.
摘要
双分子脂质膜（BLM）被建模为一个受到外加电压引起的压缩电力作用的体弹性层。对该模型的分析表明，当电应力超过临界值时，会出现压缩不稳定性。这种不稳定性倾向于挤压薄膜并使其破裂。与磷脂酰胆碱和胆固醇的测量值相比，考虑到弹性参数估计中的不确定性，预测的击穿电压显示出较好的一致性。
相似文献
1
Electrical breakdown of bimolecular lipid membranes as an electromechanical instability.双分子脂膜的电击穿作为一种机电不稳定性
Biophys J. 1973 Jul;13(7):711-24. doi: 10.1016/S0006-3495(73)86017-5.
2
Letter: Comments on "electrical breakdown of bimolecular lipid membranes as an electromechanical instability".信件：关于“双分子脂质膜的电击穿作为一种机电不稳定性”的评论
Biophys J. 1974 Feb;14(2):155-8. doi: 10.1016/S0006-3495(74)70007-8.
3
Reversible electrical breakdown of lipid bilayer membranes: a charge-pulse relaxation study.脂质双分子层膜的可逆电击穿：电荷脉冲弛豫研究。
J Membr Biol. 1979 Jul 16;48(2):181-204. doi: 10.1007/BF01872858.
4
Nonlinear electrical effects in lipid bilayer membranes. II. Integration of the generalized Nernst-Planck equations.脂质双分子层膜中的非线性电效应。II. 广义能斯特-普朗克方程的整合
Biophys J. 1969 Sep;9(9):1160-70. doi: 10.1016/S0006-3495(69)86443-X.
5
Effect of helium on membrane resistance.氦对膜电阻的影响。
Arch Int Pharmacodyn Ther. 1975 Oct;217(2):302-8.
6
The effect of pressure on the electrical breakdown in the membranes of Valonia utricularis.压力对单室大藻细胞膜电击穿的影响。
Biochim Biophys Acta. 1977 Jan 21;464(2):399-46. doi: 10.1016/0005-2736(77)90014-1.
7
[Reversible electrical breakdown of cholesterol-containing lipid bilayer membranes modified with holothurin A].[用海参毒素A修饰的含胆固醇脂质双层膜的可逆电击穿]
Biofizika. 1983 May-Jun;28(3):423-6.
8
Anomalous dielectric dispersion in bimolecular lipid membranes.双分子脂质膜中的异常介电色散。
Biochim Biophys Acta. 1970 Mar 17;203(1):17-27. doi: 10.1016/0005-2736(70)90031-3.
9
Current voltage curves of biomolecular lipid membranes.生物分子脂质膜的电流-电压曲线
Biochim Biophys Acta. 1975 Apr 21;389(1):1-12. doi: 10.1016/0005-2736(75)90380-6.
10
Formation of bimolecular membranes from lipid monolayers and a study of their electrical properties.脂质单分子层形成双分子膜及其电学性质研究。
Proc Natl Acad Sci U S A. 1972 Dec;69(12):3561-6. doi: 10.1073/pnas.69.12.3561.
引用本文的文献
1
In Vitro Assay Development to Study Pulse Field Ablation Outcome Using Solanum Tuberosum.利用马铃薯研究脉冲场消融效果的体外检测方法的建立。
Int J Mol Sci. 2024 Aug 17;25(16):8967. doi: 10.3390/ijms25168967.
2
Short-pulsed micro-magnetic stimulation of the vagus nerve.迷走神经的短脉冲微磁刺激
Front Physiol. 2022 Oct 7;13:938101. doi: 10.3389/fphys.2022.938101. eCollection 2022.
3
Electrochemotherapy: An Alternative Strategy for Improving Therapy in Drug-Resistant SOLID Tumors.电化学疗法：改善耐药实体瘤治疗的替代策略。
Cancers (Basel). 2022 Sep 5;14(17):4341. doi: 10.3390/cancers14174341.
4
Electroporation and Electrochemotherapy in Gynecological and Breast Cancer Treatment.电穿孔和电化学疗法在妇科和乳腺癌治疗中的应用。
Molecules. 2022 Apr 12;27(8):2476. doi: 10.3390/molecules27082476.
5
A Multicenter Randomized Controlled Prospective Study to Assess Efficacy of Laparoscopic Electrochemotherapy in the Treatment of Locally Advanced Pancreatic Cancer.一项评估腹腔镜电化学疗法治疗局部晚期胰腺癌疗效的多中心随机对照前瞻性研究。
J Clin Med. 2021 Sep 5;10(17):4011. doi: 10.3390/jcm10174011.
6
Microfluidic Based Physical Approaches towards Single-Cell Intracellular Delivery and Analysis.基于微流控的单细胞胞内递送与分析的物理方法
Micromachines (Basel). 2021 May 28;12(6):631. doi: 10.3390/mi12060631.
7
Clinical Phase I/II Study: Local Disease Control and Survival in Locally Advanced Pancreatic Cancer Treated with Electrochemotherapy.临床I/II期研究：电化学疗法治疗局部晚期胰腺癌的局部疾病控制和生存情况
J Clin Med. 2021 Mar 22;10(6):1305. doi: 10.3390/jcm10061305.
8
Molecular dynamics simulation of reversible electroporation with Martini force field.用 Martini 力场进行可逆电穿孔的分子动力学模拟。
Biomed Eng Online. 2019 Dec 26;18(1):123. doi: 10.1186/s12938-019-0743-1.
9
Irreversible Electroporation for the Ablation of Prostate Cancer.不可逆电穿孔用于前列腺癌消融。
Curr Urol Rep. 2019 Sep 2;20(10):63. doi: 10.1007/s11934-019-0929-x.
10
Solenoidal Micromagnetic Stimulation Enables Activation of Axons With Specific Orientation.螺线管微磁刺激能够激活具有特定方向的轴突。
Front Physiol. 2018 Jul 27;9:724. doi: 10.3389/fphys.2018.00724. eCollection 2018.
本文引用的文献
1
THE PROPERTIES OF LIPID BILAYER MEMBRANES SEPARATING TWO AQUEOUS PHASES: FORMATION OF A MEMBRANE OF SIMPLE COMPOSITION.分隔两个水相的脂质双分子层膜的特性：简单组成膜的形成。
J Mol Biol. 1964 Jan;8:148-60. doi: 10.1016/s0022-2836(64)80155-8.
2
Black lipid membranes in aqueous media: the effect of salts on electrical properties.水介质中的黑色脂质膜：盐对电性能的影响。
J Colloid Interface Sci. 1967 Jul;24(3):287-96. doi: 10.1016/0021-9797(67)90253-6.
3
Influence of electric field on the capacity of phospholipid membranes.电场对磷脂膜容量的影响。
Nature. 1966 May 28;210(5039):953-5. doi: 10.1038/210953b0.
4
The effects of a direct current potential bias on the electrical properties of bimolecular lipid membranes.直流电势偏置对双分子脂质膜电学性质的影响。
Biochim Biophys Acta. 1968 Sep 17;163(2):226-33. doi: 10.1016/0005-2736(68)90101-6.
5
Analysis of the potential-dependent changes in optical retardation in the squid giant axon.乌贼巨大轴突中光学延迟的电位依赖性变化分析。
J Physiol. 1971 Oct;218(1):205-37. doi: 10.1113/jphysiol.1971.sp009611.
6
Current models for the structure of biological membranes.生物膜结构的当前模型。
J Cell Biol. 1969 Sep;42(3):613-46. doi: 10.1083/jcb.42.3.613.
Zotero 插件