Gaillard J, Plante J, Glovaez D, Henry E, Eschapasse H
Poumon Coeur. 1979;35(2):71-5.
The authors analyzed the progress in the prevention of thrombo-embolic risk in 550 pneumonectomies divided chronologically in 4 groups : without anticoagulant treatment, with post-operative anti-vitamin K, with post-operative calcium heparinate, with pre and post-operative calcium heparinate. This study revealed the necessity of a pre-operative systematic preventive treatment : systematic, as there is no biological reason enabling the prevention of thrombosis risk. Pre-operative, because venous thrombosis and pulmonary embolism can occur very early.
作者分析了550例肺切除术患者预防血栓栓塞风险的进展情况,这些患者按时间顺序分为4组:未接受抗凝治疗组、术后使用维生素K拮抗剂组、术后使用肝素钙组、术前及术后使用肝素钙组。该研究表明,有必要进行术前系统性预防性治疗:之所以是系统性的,是因为没有生物学依据能够预防血栓形成风险;之所以是术前的,是因为静脉血栓形成和肺栓塞可能在很早的时候就会发生。