Kopf A, Charton M, Brisset J M, Veillon B, Finetti P, Duclos J M
J Chir (Paris). 1980 Feb;117(2):87-98.
Three groups of patients undergoing urological operations were given a prophylactic regimen of either subcutaneous heparin (n = 1143), antiprothrombics (n = 944) or no medication (n = 570). Results were deemed through simple clinical criteria. They were similar for the whole of patients and for some types of surgery, pecularly protatic: Anticoagulation induced a significant lowering of the frequency of thromboembolism, heparin being more efficient than antiprothrombics. It does not increase the percentage of haemorrhages. More, peridural anesthesia is not contre-indicated by heparin. However, parietal problems appear to be more frequent among heparinized patients.
三组接受泌尿外科手术的患者分别接受皮下肝素(n = 1143)、抗凝血剂(n = 944)预防方案或不接受药物治疗(n = 570)。通过简单的临床标准评估结果。在所有患者以及某些类型的手术(特别是前列腺手术)中结果相似:抗凝治疗可显著降低血栓栓塞的发生率,肝素比抗凝血剂更有效。它不会增加出血百分比。此外,肝素并不禁忌硬膜外麻醉。然而,肝素化患者出现腹壁问题的情况似乎更频繁。