英国临床化学实验室血清分析结果的比较调查。

Whitehead T P, Browning D M, Gregory A

J Clin Pathol. 1973 Jun;26(6):435-45. doi: 10.1136/jcp.26.6.435.

Since July 1969, portions of the same blood serum have been dispatched to clinical chemistry laboratories in the United Kingdom at 14-day intervals. The results of each serum survey were reported to each of the 390 participants within 11 days of their originally receiving the specimen. During the first 18 months of the survey no overall improvement in the results was seen. Therefore a summary of each laboratory's ability consistently to produce results close to the mean of the method used was calculated and reported as a single figure, the variance index, and sent to all participants at regular intervals together with a histogram distribution of the variance indices of other participants. The subsequent improvement in the overall results is described.

自1969年7月起，同一份血清样本每隔14天就会被送往英国的临床化学实验室。每次血清检测的结果都会在样本最初送达后的11天内反馈给390名参与者中的每一位。在调查的前18个月里，结果未见整体改善。因此，计算并报告了每个实验室持续得出接近所用方法平均值结果的能力的总结，以一个单一数字即方差指数呈现，并定期与其他参与者方差指数的直方图分布一起发送给所有参与者。文中描述了后续整体结果的改善情况。