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遗尿症化疗的生理和药理学基础。

Physiological and pharmacological basis for the chemotherapy of enuresis.

作者信息

Stephenson J D

出版信息

Psychol Med. 1979 May;9(2):249-63. doi: 10.1017/s0033291700030749.

DOI:10.1017/s0033291700030749
PMID:472071
Abstract

Enuresis is a disorder of micturition occuring in the absence of an organic urinary tract lesion. To understand its possible causation, the mechanisms controlling micturition are described together with the possible sites of action of various anti-enuretic agents, particularly imipramine. It is concluded that further research into the central control of micturition is required before the precise actions of centrally-acting anti-enuretic agents can be elucidated. Knowledge of these may give insight into the nature of the defect causing enuresis.

摘要

遗尿症是一种在没有器质性尿路病变情况下发生的排尿障碍。为了解其可能的病因,现将控制排尿的机制以及各种抗遗尿药物(特别是丙咪嗪)可能的作用部位一并描述。得出的结论是,在阐明中枢作用抗遗尿药物的确切作用之前,需要对排尿的中枢控制进行进一步研究。了解这些可能有助于深入了解导致遗尿症的缺陷的本质。

相似文献

1
Physiological and pharmacological basis for the chemotherapy of enuresis.遗尿症化疗的生理和药理学基础。
Psychol Med. 1979 May;9(2):249-63. doi: 10.1017/s0033291700030749.
2
Some effects of imipramine on micturition and their relevance to its anti-enuretic activity.丙咪嗪对排尿的某些影响及其与抗遗尿活性的相关性。
Neuropharmacology. 1979 Jan;18(1):33-7. doi: 10.1016/0028-3908(79)90006-6.
3
Disorders of micturition: neuropharmacologic basis and results of drug therapy.排尿障碍:神经药理学基础与药物治疗结果
Urology. 1976 Oct;8(4):316-28. doi: 10.1016/0090-4295(76)90483-0.
4
Nocturnal enuresis: comparison of the effect of imipramine and dietary restriction on bladder capacity.夜间遗尿症:丙咪嗪与饮食限制对膀胱容量影响的比较
Can Med Assoc J. 1969 Dec 13;101(12):65-8.
5
[Enuresis--symptom of delayed micturition development or an obstructive urinary tract anomaly?].[遗尿症——排尿延迟发育的症状还是尿路梗阻异常?]
Klin Padiatr. 1985 Mar-Apr;197(2):85-9. doi: 10.1055/s-2008-1033933.
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Lower urinary tract pharmacology: III. Neuropharmacologic basis for lower urinary tract dynamics.
Urology. 1977 Mar;9(3):357-63. doi: 10.1016/0090-4295(77)90368-5.
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Effect of acute or chronic administration of imipramine on spinal and supraspinal micturition reflexes in rats.急性或慢性给予丙咪嗪对大鼠脊髓和脊髓上排尿反射的影响。
J Pharmacol Exp Ther. 1989 Jan;248(1):278-85.
8
[Urodynamic assessment of enuretic children (author's transl)].遗尿症儿童的尿动力学评估(作者译)
Wien Klin Wochenschr. 1979 Nov 9;91(21):738-41.
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Polyuric and non-polyuric bedwetting--pathogenic differences in nocturnal enuresis.
Scand J Urol Nephrol Suppl. 1995;173:77-8; discussion 79.
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Neurophysiological aspects of enuresis.遗尿症的神经生理学方面。
Acta Neurol Scand. 1972;48(2):222-30. doi: 10.1111/j.1600-0404.1972.tb07543.x.