Vorlicková M, Palecek E, Sponar J
Radiat Environ Biophys. 1979 Apr 30;16(2):117-23. doi: 10.1007/BF01323219.
UV irradiation of the chromatin caused an increase of the positive circular dichroic band in the vicinity of 275 nm (corresponding to DNA) and a deepening of the negative band of proteins at about 225 nm. These changes in the circular dichroic spectrum are monotonous in the range of doses studied (less than 6 X 10(4) J.m-2). The increase of the positive circular dichroic band probably reflects the occurrence of local conformational changes in DNA, which include changes in base position (tilting, distance from helix axis) in the close neighborhood of photoproducts. The presence of photoproducts in chromatin reduces changes in its circular dichroic spectra with temperature.
对染色质进行紫外线照射会导致在275纳米附近（对应于DNA）的正圆二色性带增加，以及在约225纳米处蛋白质的负带加深。在所研究的剂量范围内（小于6×10⁴ J·m⁻²），圆二色光谱的这些变化是单调的。正圆二色性带的增加可能反映了DNA中局部构象变化的发生，其中包括光产物紧邻区域内碱基位置的变化（倾斜、与螺旋轴的距离）。染色质中光产物的存在会降低其圆二色光谱随温度的变化。
